Recent news from Illuminating the Druggable Genome Consortium include: Announcement of an open, joint symposium with Open Targets in Hinxton, UK on Nov. 15th, 2019; Highlight of IDG resources from a recent article by IDG members from UNC on their VEGAS platform; IDG funding opportunities; New batch of Target Watch articles in NRDD.


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Joint symposium with Open Targets

IDG have joined forces with Open Targets to host an exciting symposium on Nov. 15th, 2019 at the Wellcome Genome Campus in Hinxton, UK. Speakers from both groups will present talks focused on ‘Finding Targets For Drug Discovery’. Plus, our keynote speaker, Dr. Michael Sundstrom from Karolinska Institute, will present updates from the Structural Genomics Consortium.  Please join us for this engaging meeting and register by clicking on the link below.

Additionally, the IDG speakers will coordinate individual meetings on the day before the open symposium, Nov. 14th, 2019.  If interested, please contact

Registration for ‘Finding Targets For Drug Discovery’ >>

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Highlighting IDG resources

The DRGC-GPCR group lead by Dr. Bryan Roth at UNC recently published a paper in Cell on an evolutionary new platform for illuminating understudied proteins - Viral Evolution of Genetically Actuating Sequences (VEGAS).  They have applied this technology to elucidate allosteric nanobodies binding to active-state GPCR.  Furthermore, the IDG resources developed by this group for this paper are made available via AddGene.

VEGAS paper >>
IDG resources from VEGAS paper available via AddGene >>
Barcode images with links to articles

Target Watch in NRDD

New set of IDG Target Watch in Nature Reviews Drug Discovery are available:

Funding Opportunities

NIH have announced new funding opportunity associated with IDG for “Pilot Projects Investigating Understudied G Protein-Coupled Receptors, Ion Channels, and Protein Kinases (R03 Clinical Trial Not Allowed)”. Due date is October 28, 2019.

Link to RFA on NIH site >>

Find us online

DRGC: U24 DK116195, U24 DK116204, U24 DK116214
KMC: U24 CA224370, U24 CA224260;  RDOC: U24 TR002278
CEIT: U01 CA239106, U01 CA239108, U01 CA239069
More IDG details on our IDG site or via NIH Common Fund site.
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IDG Newsletter Vol. 2, 2019-08-01

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Illuminating the Druggable Genome · 1 University of New Mexico · Albuquerque, NM 87131-0001 · USA

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