In the Literature, cont.
Predicting Cognitive Executive Functioning with Polygenic Risk Scores for Psychiatric Disorders
Chelsie E. Benca et al.
Because executive function (EF) deficits are associated with most psychiatric disorders, EFs have been proposed as an endophenotype for such disorders. This study found no evidence that EFs are better endophenotypes than currently used measures more similar to these disorders. However, larger sample sizes will be important in examining this relationship further.
Genome-Wide Association Analyses of Sleep Disturbance Traits Identify New Loci and Highlight Shared Genetics With Neuropsychiatric and Metabolic Traits
Jacqueline M. Lane et al.
Chronic sleep disturbances affect 25–30% of adults worldwide and are associated with cardiometabolic diseases, psychiatric disorders and all-cause mortality. This study discovered genetic loci associated with insomnia symptoms, and genetic correlations between longer sleep duration and schizophrenia risk.
Heritability of Behavioral Problems in 7-Year Olds Based on Shared and Unique Aspects of Parental Views
Iryna O. Fedko et al.
Parent assessments often form the backbone of child psychopathology studies, and maternal ratings are the most common metric used. Parents are not always in agreement on the behavior of their child, though, so adding paternal observations may provide additional information that increases a study’s power.
Genetic and Environmental Sources of Implicit and Explicit Self-Esteem and Affect: Results from a Genetically Sensitive Multi-group Design
Stefan Stieger et al.
Researchers frequently utilize measures of implicit (i.e., automatic, spontaneous) evaluations. This study suggests that implicit and explicit evaluations of self-esteem and affect share a common genetic core, which aligns with the motivation and opportunity as determinants (MODE) model.
The Role of Genes and Environment in Degree of Partner Self-Similarity
James M. Sherlock et al.
The processes underlying romantic partner choice are remarkably complex and have been largely resistant to scientific explanation. One consistent finding is that, on average, members of romantic dyads tend to be more alike than would be expected by chance. This study revealed that very little of the variation in the tendency to assortatively mate across 14 traits was due to genetic effects (7%) or the shared environment.
The Influence of Genotype Information on Psychiatrists' Treatment Recommendations: More Experienced Clinicians Know Better What to Ignore
Alan McMichael et al.
A patient's genetic information may be used to predict their response to therapy; such information, however, becomes redundant once a clinician knows the patient's actual response to treatment.Clinicians should be cautious about allowing a patient's genetic information to carry unnecessary weight in clinical decision making.