Mapping the Structure and Function of the Human Brain: Potential Benefits to Neurotoxicology
Our current In the Spotlight summarizes important aspects of two large U.S. government programs that are addressing the current global challenge to map and understand the structure and function of the human brain, the Human Connectome Project and the BRAIN Initiative.
Of interest to the AltTox and toxicology communities is whether the current and emerging breakthroughs in human brain research will lead to better in vitro and in silico tools for predicting human neurotoxicity. Such predictive tools would be of great benefit to public health, since prevention of some types of neurological disorders may be the best (and at least for now, the only) treatment.
At present, there is no path forward to identify and utilize discoveries resulting from these large brain research programs for applications in neurotoxicology and neurotoxicity testing. This article hopes to stimulate further discussion in this direction.
The article also includes expert commentaries on this topic from Dr. Thomas Knudsen of the U.S. EPA and Dr. Remco Westerink of Utrecht University.
Read the full article here.