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January 2016

AltTox Editorial Board and Management Team members at SOT 2016

A number of AltTox’s Management Team and Editorial Board members will be participating as presenters or session chairs at the annual Society of Toxicology meeting in New Orleans, March 13-17.  A partial list of presentations follows. Please check our Community Blog for updates as the meeting date nears.

This year, AltTox will share an informational booth with our site co-sponsor, the Human Toxicology Project Consortium (HTPC) at the ToxExpo center. Drop by booth #1402 to enter our t-shirt raffle!

  • Kristie Sullivan, “Introduction to Adverse Outcome Pathways and International Activities Guiding AOP Development.” Session: Continuing Education on “Adverse Outcome Pathway (AOP) Development and Evaluation Continuing Education,” Sunday, March 13, 8:15 AM–12:00 PM.
  • Martin Stephens, “Evidence-Based Approaches for Enhancing the Reproducibility of Toxicological Studies.” Session: Scientific Reproducibility: Does This Pose a Problem for 21st Century Toxicology? Monday, March 14, 9:30 AM to 12:15 PM.
  • Bas Blaauboer, “Introduction.” Session: Safety Assessment of Topically Exposed Cosmetic Ingredients: Lessons Learned, Tuesday, March 15, 2:00 PM to 4:45 PM.
  • Grace Patlewicz, “Introduction” and “Do Tox21 Approaches Such as Data from ToxCast Enhance Existing OECD Chemical Categories?” Session: Building Scientific Confidence in the Development and Evaluation of Read- Across for Regulatory Purposes Using Tox21 Approaches, Tuesday, March 15, 2:00 PM to 4:45 PM.
  • William Mundy, “Evaluating the Ability of In Vitro Assays Based on Key Events in Neurodevelopment to Predict Developmental Neurotoxicity (DNT).” Session: Screening Chemicals for Neurotoxicity Outcomes, Wednesday, March 16, 9:30 AM to 12:15 PM.
  • Catherine Willett, "Regulatory Acceptance of Non-standard Toxicological Methods through Increased use of Integrated Approaches to Testing and Assessment (IATA)." Poster Session: Regulation and Policy, Wednesday, March 16, 1:15 PM to 4:45 PM (Abstract #3003/Poster #P143).
  • George Daston, “Selecting Cell Types that Provide Transcriptomic Data Over a Broad Range of Modes of Action.” Session: Which Human Cell Lines Should I Use? Choosing the Appropriate Biological Systems for High-Throughput Toxicity Testing, Thursday, March 17, 9:30 AM to 12:15 PM.
  • Catherine Willett will also give an update on Human Toxicology Project Consortium (HTPC) activities at a satellite meeting co-sponsored by the HTPC, the Center for Alternatives to Animal Testing (CAAT), and the Human Toxome Project Consortium, "Updates on Activities Related to 21st Century Toxicology and Related Efforts: Invited Presentations and Open Microphone," Thursday, March 17, 12:30 PM–4:00 PM. This satellite meeting will take place at the Hilton New Orleans Riverside. Box lunches will be available for those who have pre-registered; to register, contact Jamie DeRita at CAAT.

AOP Wiki Seminar at SOT

HTPC and the Physicians Committee for Responsible Medicine (PCRM) will co-sponsor a "hands-on seminar," Creating an Adverse Outcome Pathway in the AOP Wiki, Tuesday, March 15 from 5:00 PM–7:00 PM in the Belle Chasse Room of the Hilton New Orleans Riverside (2 Poydras Street). Participants will gain experience entering an Adverse Outcome Pathway. Dr. Steven Edwards of the US EPA will provide a brief introduction into the AOP Wiki, and course instructors will be available to provide guidance and answer questions as participants work through and present a case example. Please indicate your interest in attending by contacting Kristie Sullivan at ksullivan@pcrm.org, to ensure the appropriate number of facilitators and laptop availability. Participants will work in groups of three; please indicate when you register whether you will be able to bring a Wi-Fi enabled laptop. Participation in the AM03 CE course, or a basic understanding of AOP guidelines and practices, is required, as background presentations will not be provided. Light refreshments served.
SOT Ancillary Meeting: Priorities and Opportunities for Replacement of Animal Tests: A Discussion with NICEATM and ICCVAM Leadership (Monday, March 16, 5:00-6:00 PM)

This meeting will provide a forum for discussion with Dr. Warren Casey, director of the U.S. National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and Dr. Anna Lowit, senior scientist at the U.S. Environmental Protection Agency (U.S. EPA) and co-chair of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). ICCVAM, with support from NICEATM, facilitates the development, validation, and regulatory acceptance of new and revised regulatory test methods that support the 3Rs. Following a brief overview, this meeting is intended to be an open discussion of the challenges and opportunities to replace current regulatory requirements using animals. Participants are asked to come prepared to share experiences and perspectives on near-term opportunities for the global replacement of animal-based toxicology test methods. Specific examples of challenges to the implementation of alternatives within your organization are encouraged.

The meeting will take place Monday, March 14, from 5:00-6:00 PM in the Belle Chasse Room, Hilton New Orleans Riverside. The meeting is co-sponsored by the Physicians Committee for Responsible Medicine (PCRM), PETA International Science Consortium, Ltd (PISC), and the Human Toxicology Project Consortium (HTPC).


Pan-American Conference on Alternatives: Abstract deadline extended to January 31

The Pan-American Conference on Alternatives - April 12-14, in Baltimore, Maryland - will bring together experts and stakeholders from across the Americas, with a focus on the Six Rs: Replacement, Reduction, Refinement, Read-across, Relevance, and Roadmaps. This event promises to fill up quickly, as it will be limited to 300 participants on a first-come, first-served basis. Please note that there are no fees required to attend this conference. The organizers are currently working on offers for lodging, food, and social events, which will have to be born by the participants.

The deadline for submitting abstracts has been extended to January 31.

Registration and abstract submission details are available here: http://caat.jhsph.edu/programs/workshops/PanAmerican/index.html


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Upcoming Events


FRAME Training School in Experimental Design
February 1-3, Voss, Norway

Cell Culture 2016
February 2-4, London, UK

High-Content Analysis & Phenotypic Screening
February 11-12, San Diego, California

Predictive Toxicology Summit
February 16-17, London, UK

International Conference on Environmental Mutagenesis, Carcinogenesis, and Health
February 16-17, Amritsar, India

Strategies and Approaches for In Vitro to In Vivo Extrapolation
February 17-18, Research Triangle Park, North Carolina

CAAT-Europe and Cefic-LRI Workshop 2016: Good Read-across Practices: Making it Work for You!
February 26, Brussels, Belgium

OpenTox Basel
March 2, Basel, Switzerland

Bio Barriers 2016
March 7-9, Saarbrücken, Germany

SOT 55th Annual Meeting
March 13–17, New Orleans, Louisiana

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