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Good morning. 

I am pleased to provide you with a some very positive news stemming from our current pre-clinical trials. This morning we distributed a media release announcing the successful dosing of our Quicksome™ rapid dissolve oral strip and microparticle technology for the drug ivermectin.
 
The successful ivermectin dosing was completed without the use of needles on canines for two unique Quicksome™ technology applications with no adverse events.
 
As previously shared, Ivermectin is an antiparasitic drug that is administered to billions of livestock and companion animals annually and to humans to treat various parasitic infestations, including development of broader applications to protect against COVID-19 and the control of malaria.  Ivermectin is also widely used and available as an effective in vitro treatment against HIV, dengue, Zika virus, and others.
 
With the successful dosing of these two product forms, the Company anticipates receiving the complete pharmacokinetic data from the ivermectin pre-clinical trials within the next two weeks.  We anticipate that the pharmacokinetic data will successfully document superior movement of the ivermectin drug into, through, and out of the body, simultaneously addressing a multitude of key efficacy challenges, such as low bioavailability, high absorption variability and poor dosage control.
 
The Company believes that successful ivermectin dosing in the pre-clinical trial environment demonstrates the ability for the Quicksome™ platform to be adapted to commercially viable delivery products for both veterinary and human medical applications.
 
I would encourage you to read the full media release on our company website - https://www.mountainvalleymd.com/investor.
 
We look forward to sharing some more positive updates stemming from this progress and our Quicksome™ technology in the coming weeks.  Wishing you continued health and safety and a wonderful weekend!

Sincerely yours, 

Dennis

Dennis Hancock
President & CEO
 
Mountain Valley MD
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