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Dear all, 

Welcome to this first edition of our monthly newsletter with all updates and latest news regarding the SPOT-studies! The SPOT-studies aim to improve the care for women with preeclampsia in Ghana. 

SPOT-studies overview

  1. To externally validate the fullPIERS and miniPIERS prediction models, and develop a simple, user friendly, numeric Severe Pre-eclampsia adverse Outcome Triage (SPOT) score to assist clinical decision making in severe early pre-eclampsia (SPOT-VAL).
  2. To quantify the relationship between fetal (and maternal) APOL1 status and preeclampsia and assess whether this can predict pre-eclampsia (SPOT-BIO).
  3. To understand the views on ‘good care’ of various stakeholders in the care of Hypertension Disorders in Pregnancy (HDP): health professionals, health management and pregnant women themselves.
  4. To assess impact of SPOT-score combined with shared-decision making tool implementation (SPOT-impact).

SPOT-study Timeline


SPOT-BIO coordinator Nana Ampofo: has successfully completed the Clinical Research Monitoring summer school in Utrecht, Netherlands.

Start Daily Krijnen: she joined our research group as coordinator and will be conducting her own substudy on mental health issues.
Start Mona Zeevaert: she recently joined the Cesarean section study group at Korle-Bu Teaching Hospital, and will support the normotensive cohort study activities as part of a collaboration between our two groups.


SPOT-BIO launched in 3 hospitals: Greater Accra Regional Hospital, Korle-Bu Teaching Hospital and La General Hospital. Eastern Region Hospital Koforidua will start this week with recruitments.

Dutch Research Council Grant for SPOT-impact
Research on Routes for Consortia (NWA-ORC) granted a total of €1.3 million to the SPOT-Impact study, which aims to develop a shared decision making tool for risk assessment for pregnant women with preeclampsia in Ghana. 

Consortium members: UMC Utrecht, University of Amsterdam, Ghana Health Services, University of Ghana, Korle-Bu Teaching Hospital, University of Tennessee, University of British Columbia, Share-Net, FIGO, and the Action of Preeclampsia Ghana (APEC-GH)

Recruitment process

Research assistants and nurses have been recruited and trained for the fetal sample collection and follow up in Ridge, Korle-Bu, La General and Koforidua.

                                               SPOT-VAL:                 SPOT-BIO
Ridge Hospital:                       311 women                 96 women
Korle Bu Teaching Hospital:   232 women                 36 women
La General Hospital:              169 women                  30 women
Lekma Hospital:                       17 women                                   
Tema Hospital:                         41 women                                   
Koforidua:                                  8 women                    8 women

Total:                                      778 women

Almost there! Soon we will start with the recruitment of the control group which includes 1600 normotensive women.

Meet the Team

Ghana Health Services, Accra, Ghana
  • Dr. Emmanuel K. Srofenyoh, MBChB MPhil FWACS
  • Dr. Fred Pobee, MBChB FWACS
  • Dr. Sylvia Deganus, MBChB MPH FWACS
  • Dr. Hellen Akaba, MBChB MPH FWACS
  • Dr. Ama Tamatey, MBChB FWACS
  • Dr. Patrick Aboagye, MB-BCH MPH Dip. RH
  • Dr. Kwame Anim-Boamah, MBChB MBA FWACS
  • Prof. Dr. Irene Agyepong, MBChB PhD
  • Dr. Evelyn K. Ansah, MBChB PhD
  • Dr. Edward Antwi, MBChB PhD
  • Dr. Maame Yaa Essel, MBChB
  • Mr. Nana K.A. Ampofo, BSc

UMC Utrecht, The Netherlands

  • Dr. Joyce Browne, MD PhD
  • Prof. Dr. Diederick Grobbee, MD PhD FESC
  • Dr. Kerstin Klipstein-Grobusch, PhD
  • Prof. Dr. Arie Franx, MD PhD
  • Ms. Ilja van der Geest, Ms. Tessa van Otterloo, Ms. Lisa Kraneburg, Ms. Connie Rees, Ms. Daily Krijnen, Ms. Mona Zeevaert

Korle-Bu Teaching Hospital

  • Dr. Kwame Adu-Bonsaffoh, MD MPhil FWACS, University of Ghana Medical School


University of British Columbia, Vancouver

  • Dr. Beth Payne, PhD


University of Tennessee (APOL1 substudy)

  • Dr. Claire Simpson, PhD
  • Prof. Robert Davis, MD MPH
  • Ms. Alana Tonya Smith, Sr. RA


H3Africa Kidney Network
(APOL1 substudy)

  • Dr. Vincent Boima, MBChB
  • Dr. Dwoama Adu, MBChB
  • Dr. Charlotte Osafo, MBChB


University of Ghana, Noguchi

  • Dr. Mary Amoakoh-Coleman, MBChB PhD
  • Dr. Daniel Arhinful, PhD
  • Dr. Hannah Brown Amoakoh (joint collaboration with UMCU)


University of Amsterdam
(Quality of care)

  • Dr. Bregje de Kok, Dr. Trudie Gerrits, Ms. Asra Vestering

Contact us

Dr. Joyce Browne
Dr. Joyce Browne
Dr. Emmanuel Srofenyoh
Dr. Emmanuel Srofenyoh
Prof. Robert Davis
Prof. Robert Davis
Copyright © 2019 SPOT study, All rights reserved.

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